diff --git a/Code/Framework/AzCore/AzCore/Component/Component.cpp b/Code/Framework/AzCore/AzCore/Component/Component.cpp
index f336b9e1a1..498e4d03d3 100644
--- a/Code/Framework/AzCore/AzCore/Component/Component.cpp
+++ b/Code/Framework/AzCore/AzCore/Component/Component.cpp
@@ -174,7 +174,11 @@ namespace AZ
     //=========================================================================
     void ComponentDescriptor::ReleaseDescriptor()
     {
-        AZ::Interface<AZ::ComponentApplicationRequests>::Get()->UnregisterComponentDescriptor(this);
+        AZ::ComponentApplicationRequests* componentApplication = AZ::Interface<AZ::ComponentApplicationRequests>::Get();
+        if (componentApplication != nullptr)
+        {
+            componentApplication->UnregisterComponentDescriptor(this);
+        }
         delete this;
     }
 } // namespace AZ
diff --git a/Code/Framework/AzCore/AzCore/Component/Entity.cpp b/Code/Framework/AzCore/AzCore/Component/Entity.cpp
index 6796bccb2b..b7c161b53c 100644
--- a/Code/Framework/AzCore/AzCore/Component/Entity.cpp
+++ b/Code/Framework/AzCore/AzCore/Component/Entity.cpp
@@ -112,7 +112,11 @@ namespace AZ
         {
             EBUS_EVENT(EntitySystemBus, OnEntityDestruction, m_id);
             EBUS_EVENT_ID(m_id, EntityBus, OnEntityDestruction, m_id);
-            AZ::Interface<AZ::ComponentApplicationRequests>::Get()->RemoveEntity(this);
+            AZ::ComponentApplicationRequests* componentApplication = AZ::Interface<AZ::ComponentApplicationRequests>::Get();
+            if (componentApplication != nullptr)
+            {
+                componentApplication->RemoveEntity(this);
+            }
             m_stateEvent.Signal(State::Init, State::Destroying);
         }
 
@@ -216,14 +220,22 @@ namespace AZ
 
         EBUS_EVENT_ID(m_id, EntityBus, OnEntityActivated, m_id);
         EBUS_EVENT(EntitySystemBus, OnEntityActivated, m_id);
-        AZ::Interface<AZ::ComponentApplicationRequests>::Get()->SignalEntityActivated(this);
+        AZ::ComponentApplicationRequests* componentApplication = AZ::Interface<AZ::ComponentApplicationRequests>::Get();
+        if (componentApplication != nullptr)
+        {
+            componentApplication->SignalEntityActivated(this);
+        }
     }
 
     void Entity::Deactivate()
     {
         AZ_PROFILE_FUNCTION(AZ::Debug::ProfileCategory::AzCore);
 
-        AZ::Interface<AZ::ComponentApplicationRequests>::Get()->SignalEntityDeactivated(this);
+        AZ::ComponentApplicationRequests* componentApplication = AZ::Interface<AZ::ComponentApplicationRequests>::Get();
+        if (componentApplication != nullptr)
+        {
+            componentApplication->SignalEntityDeactivated(this);
+        }
         EBUS_EVENT_ID(m_id, EntityBus, OnEntityDeactivated, m_id);
         EBUS_EVENT(EntitySystemBus, OnEntityDeactivated, m_id);