diff --git a/Gems/AWSCore/Code/Tools/ResourceMappingTool/controller/view_edit_controller.py b/Gems/AWSCore/Code/Tools/ResourceMappingTool/controller/view_edit_controller.py
index 7e058e6a4e..54d0a29fea 100755
--- a/Gems/AWSCore/Code/Tools/ResourceMappingTool/controller/view_edit_controller.py
+++ b/Gems/AWSCore/Code/Tools/ResourceMappingTool/controller/view_edit_controller.py
@@ -105,6 +105,8 @@ class ViewEditController(QObject):
 
     def _create_new_config_file(self) -> None:
         configuration: Configuration = self._configuration_manager.configuration
+        self._set_default_region(configuration)
+
         try:
             new_config_file_path: str = file_utils.join_path(
                 configuration.config_directory, constants.RESOURCE_MAPPING_DEFAULT_CONFIG_FILE_NAME)
@@ -117,6 +119,15 @@ class ViewEditController(QObject):
 
         self._rescan_config_directory()
 
+    def _set_default_region(self, configuration: Configuration):
+        default_region = configuration.region
+        if not default_region or default_region == 'aws-global':
+            self.set_notification_frame_text_sender.emit(
+                notification_label_text.VIEW_EDIT_PAGE_CREATE_NEW_CONFIG_FILE_NO_DEFAULT_REGION_MESSAGE)
+            logger.warning(notification_label_text.VIEW_EDIT_PAGE_CREATE_NEW_CONFIG_FILE_NO_DEFAULT_REGION_MESSAGE)
+
+            configuration.region = constants.RESOURCE_MAPPING_DEFAULT_CONFIG_FILE_REGION
+
     def _delete_table_row(self) -> None:
         indices: List[QModelIndex] = self._table_view.selectedIndexes()
         self._proxy_model.remove_resources(indices)
diff --git a/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/constants.py b/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/constants.py
index 857925499b..94846fc6b5 100755
--- a/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/constants.py
+++ b/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/constants.py
@@ -24,6 +24,7 @@ AWS_RESOURCE_REGIONS: List[str] = ["us-east-2", "us-east-1", "us-west-1", "us-we
 # Default client&server config file name
 RESOURCE_MAPPING_CONFIG_FILE_NAME_SUFFIX: str = "_aws_resource_mappings.json"
 RESOURCE_MAPPING_DEFAULT_CONFIG_FILE_NAME: str = "default" + RESOURCE_MAPPING_CONFIG_FILE_NAME_SUFFIX
+RESOURCE_MAPPING_DEFAULT_CONFIG_FILE_REGION: str = "us-east-1"
 
 # View related constants
 SEARCH_TYPED_RESOURCES_VERSION: str = "Import AWS Resources"
diff --git a/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/notification_label_text.py b/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/notification_label_text.py
index 4fbff42aba..ecd6d8282c 100755
--- a/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/notification_label_text.py
+++ b/Gems/AWSCore/Code/Tools/ResourceMappingTool/model/notification_label_text.py
@@ -5,6 +5,8 @@ For complete copyright and license terms please see the LICENSE at the root of t
 SPDX-License-Identifier: Apache-2.0 OR MIT
 """
 
+from model import constants
+
 NOTIFICATION_LOADING_MESSAGE: str = "Loading..."
 
 ERROR_PAGE_OK_TEXT: str = "OK"
@@ -21,6 +23,12 @@ VIEW_EDIT_PAGE_RESCAN_TEXT: str = "Rescan"
 VIEW_EDIT_PAGE_CONFIG_FILES_PLACEHOLDER_TEXT: str = "Found {} config files"
 VIEW_EDIT_PAGE_SEARCH_PLACEHOLDER_TEXT: str = "Search by Key Name, Type, Name/ID, Account ID or Region"
 VIEW_EDIT_PAGE_IMPORT_RESOURCES_PLACEHOLDER_TEXT: str = "Import Additional Resources"
+VIEW_EDIT_PAGE_CREATE_NEW_CONFIG_FILE_NO_DEFAULT_REGION_MESSAGE: str = \
+    f"Resource mapping file {constants.RESOURCE_MAPPING_DEFAULT_CONFIG_FILE_NAME} is created"\
+    f" with {constants.RESOURCE_MAPPING_DEFAULT_CONFIG_FILE_REGION} as the default region. "\
+    f"See <a href=\"https://docs.o3de.org/docs/user-guide/gems/reference/aws/aws-core/configuring-credentials/\">"\
+    f"<span style=\"color:#4A90E2;\">documentation</span></a> "\
+    f"for configuring the AWS credentials and default region."
 
 VIEW_EDIT_PAGE_SELECT_CONFIG_FILE_MESSAGE: str = "Please select the Config file you would like to view and modify..."
 VIEW_EDIT_PAGE_NO_CONFIG_FILE_FOUND_MESSAGE: str = \
diff --git a/Gems/AWSCore/Code/Tools/ResourceMappingTool/tests/unit/controller/test_view_edit_controller.py b/Gems/AWSCore/Code/Tools/ResourceMappingTool/tests/unit/controller/test_view_edit_controller.py
index d76ae12940..f854d2cd68 100755
--- a/Gems/AWSCore/Code/Tools/ResourceMappingTool/tests/unit/controller/test_view_edit_controller.py
+++ b/Gems/AWSCore/Code/Tools/ResourceMappingTool/tests/unit/controller/test_view_edit_controller.py
@@ -482,6 +482,7 @@ class TestViewEditController(TestCase):
         mock_json_utils.create_empty_resource_mapping_file.assert_called_once()
         mock_file_utils.find_files_with_suffix_under_directory.assert_called_once()
         self._mocked_view_edit_page.set_config_files.assert_called_with(expected_config_files)
+        self._test_view_edit_controller.set_notification_frame_text_sender.emit.assert_called_once()
 
     @patch("controller.view_edit_controller.file_utils")
     @patch("controller.view_edit_controller.json_utils")
@@ -496,7 +497,7 @@ class TestViewEditController(TestCase):
         mock_file_utils.join_path.assert_called_once()
         mock_json_utils.create_empty_resource_mapping_file.assert_called_once()
         mock_file_utils.find_files_with_suffix_under_directory.assert_not_called()
-        self._test_view_edit_controller.set_notification_frame_text_sender.emit.assert_called_once()
+        assert len(self._test_view_edit_controller.set_notification_frame_text_sender.emit.mock_calls) == 2
 
     @patch("controller.view_edit_controller.file_utils")
     def test_page_rescan_button_post_notification_when_find_files_throw_exception(