diff --git a/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Android/Vulkan/AzslcHeader.azsli b/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Android/Vulkan/AzslcHeader.azsli
index 54c9430f87..0cab4d7a38 100644
--- a/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Android/Vulkan/AzslcHeader.azsli
+++ b/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Android/Vulkan/AzslcHeader.azsli
@@ -16,6 +16,11 @@
 
 static const float4 s_AzslDebugColor = float4(165.0 / 255.0, 30.0 / 255.0, 36.0 / 255.0, 1);
 
-// Uniform limitation need to be taken into consideration for mobile devices
+// Uniform limitation need to be taken into consideration for mobile devices. This would help alleviate device lost errors if the constant buffer
+// size overshoots the device's memory constraints. An example is a large number of constant buffers associated with mesh instances that would result in device lost,
+// but otherwise OK on PC. We can separate out the number of instances for the different platforms with this define.
 // [ATOM-14949]
-#define AZ_TRAIT_CONSTANT_BUFFER_LIMITATIONS 1
\ No newline at end of file
+#define AZ_TRAIT_CONSTANT_BUFFER_LIMITATIONS 1
+
+// Different constant buffer alignment on platforms
+#define AZ_TRAIT_CONSTANT_BUFFER_ALIGNMENT      16
diff --git a/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Windows/Vulkan/AzslcHeader.azsli b/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Windows/Vulkan/AzslcHeader.azsli
index b620c0d696..58395ef6a4 100644
--- a/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Windows/Vulkan/AzslcHeader.azsli
+++ b/Gems/Atom/Asset/Shader/Code/AZSL/Platform/Windows/Vulkan/AzslcHeader.azsli
@@ -12,3 +12,7 @@
 */
 
 static const float4 s_AzslDebugColor = float4(165.0 / 255.0, 30.0 / 255.0, 36.0 / 255.0, 1);
+
+
+// Different constant buffer alignment on platforms
+#define AZ_TRAIT_CONSTANT_BUFFER_ALIGNMENT      128
\ No newline at end of file